Document Detail

Some mathematical problems of excitability.
MedLine Citation:
PMID:  2082914     Owner:  NLM     Status:  MEDLINE    
The description of the electrical behaviour of nerve and muscle is one of the most quantitative areas of cellular physiology. There are detailed biophysical measurements of currents and potentials, that may be summarised as Master equations or stochastic differential equations for membrane channel and noise recordings, and nonlinear differential equations for macroscopic voltage clamp recordings. Propagation in excitable media is described by nonlinear reaction-diffusion equations. Computational approaches can provide solutions to these equations, but without qualitative studies on simplified caricatures contribute little to mathematical or physiological understanding.
A V Holden
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Biomedica biochimica acta     Volume:  49     ISSN:  0232-766X     ISO Abbreviation:  Biomed. Biochim. Acta     Publication Date:  1990  
Date Detail:
Created Date:  1991-05-08     Completed Date:  1991-05-08     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8304435     Medline TA:  Biomed Biochim Acta     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  651-60     Citation Subset:  IM    
Department of Physiology, The University, Leeds, U.K.
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MeSH Terms
Axons / drug effects,  physiology*
Calcium / pharmacology
Membrane Potentials*
Potassium Channels / drug effects
Reg. No./Substance:
0/Potassium Channels; 7440-70-2/Calcium

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