Document Detail

Some factors affecting the utility of bovine blood as a control material in lead-screening programs.
MedLine Citation:
PMID:  630716     Owner:  NLM     Status:  MEDLINE    
Bovine blood is used frequently as control material in interlaboratory comparisons for blood-lead analysis, but an erythrocyte protoporphyrin control material is needed. We present data on the rate of changes in blood lead and erythrocyte protoporphyrin in steers fed lead acetate. We also show, by comparison of fluorescence spectra with those of known compounds, that most of the porphyrin in lead-burdened steers probably exists as free protoporphyrin IX along with some zinc-complexed protoporphyrin IX. Bovine blood is suitable as an erythrocyte protoporphyrin control material for laboratories using acid extraction procedures, but not for the proficiency testing of laboratories using hematofluorometers.
Z Penton; G Bissell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  24     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-05-20     Completed Date:  1978-05-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  504-6     Citation Subset:  IM    
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MeSH Terms
Cattle / blood*
Erythrocytes / analysis
Lead / blood*
Lead Poisoning / blood,  diagnosis
Protoporphyrins / blood
Quality Control
Spectrometry, Fluorescence
Reg. No./Substance:
0/Protoporphyrins; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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