| Some effects of maternal pethidine administration on the newborn. | |
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MedLine Citation:
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PMID: 6401429 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of maternal pethidine administration (100 mg intramuscularly) were investigated in 150 infants at 1-2 h after birth, 95 infants whose mothers had not received pethidine served as a control group. Pethidine administration showed no effect on pH or PCO2 of cord blood and neonatal arterial blood at 1-2 h after birth if the time interval between pethidine administration and delivery was less than or equal to 1 h. However, when the interval was greater than 1 h: umbilical vein blood PCO2 was higher; neonatal arterial blood PCO2 was higher; neonatal baseline heart rate was higher, although long-term variability was similar; the percentage time spent crying was considerably reduced compared with the corresponding values in the control group. The long-term effects of pethidine are unknown but the adverse neonatal factors particularly if the time interval between administration of the drug and delivery is greater than 1 h should be kept in mind. |
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Authors:
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G Rooth; A Lysikiewicz; R Huch; A Huch |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British journal of obstetrics and gynaecology Volume: 90 ISSN: 0306-5456 ISO Abbreviation: Br J Obstet Gynaecol Publication Date: 1983 Jan |
Date Detail:
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Created Date: 1983-03-11 Completed Date: 1983-03-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7503752 Medline TA: Br J Obstet Gynaecol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 28-33 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carbon Dioxide
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blood Female Heart Rate / drug effects Humans Hydrogen-Ion Concentration Infant, Newborn* Maternal-Fetal Exchange Meperidine / pharmacology* Oxygen / blood Pregnancy Time Factors |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 57-42-1/Meperidine; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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