| Some considerations on the safety evaluation of nonviral microbial pesticides. | |
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MedLine Citation:
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PMID: 6601535 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The tactics and rationale of maximum challenge safety tests for nonviral microbial pesticides have been reviewed. Maximum challenge tests and a tier approach to data collection for regulatory purposes offer the best opportunities to detect the acute effects of entomopathogenic organisms in mammals. Premature condemnation of promising organisms that are based on incomplete results of maximum challenge tests must be avoided. Further investigations should be conducted on the role of mammalian immune response in resistance to entomopathogenic organisms and on the value of medium- or long-term exposure tests. |
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Authors:
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J A Shadduck |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bulletin of the World Health Organization Volume: 61 ISSN: 0042-9686 ISO Abbreviation: Bull. World Health Organ. Publication Date: 1983 |
Date Detail:
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Created Date: 1983-06-17 Completed Date: 1983-06-17 Revised Date: 2010-10-26 |
Medline Journal Info:
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Nlm Unique ID: 7507052 Medline TA: Bull World Health Organ Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 117-28 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bacillus Bacillus thuringiensis Eukaryota Mammals Pest Control, Biological* Safety |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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