Document Detail

Some General Considerations about the Clinicopathologic Aspects of Soft Tissue Tumors in Children and Adolescents.
MedLine Citation:
PMID:  22375909     Owner:  NLM     Status:  Publisher    
Abstract Soft tissue tumors in children and adolescents are an important group of neoplasms, pseudoneoplasms, and tumefactive malformations with some distinctive clinicopathologic, genetic, syndromic and therapeutic implications. In addition to the basic pathologic examination, there is the availability of diagnostic adjuncts in various settings based upon the histopathologic features in order to facilitate and/or corroborate a diagnosis. Immunohistochemistry, cytogenetics, molecular genetics and an ever increasing array of new technologies are available to address specific diagnostic questions and even potential therapeutic strategies. This review focuses upon some of the unique aspects of soft tissue tumors in children including the classification, approach to the diagnosis, grading, clinical and pathologic staging, therapy-related changes, pathogenesis and risk factors.
Cheryl M Coffin; Rita Alaggio; Louis P Dehner
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-29
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  -     ISSN:  1093-5266     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
a Vanderbilt Medical Center, Department of Pathology.
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