Document Detail

Somatostatin-like peptide and regeneration capacities in planarians.
MedLine Citation:
PMID:  2881839     Owner:  NLM     Status:  MEDLINE    
The presence of a neuropeptide immunologically related to somatostatin (SRIF) has been investigated in the neurosecretory cells of two regenerating planarian species (Dugesia lugubris and Dendrocoelum lacteum). A correlation has been shown between the discharge of the SRIF-like-immunoreactive cells during the first hours after amputation and the capacity to regenerate, and between the persistence of numerous positive cells and the lack of regeneration. These results suggest that somatostatin might play a regulatory (inhibitory) role on the cellular proliferation which leads to the blastema edification.
A Bautz; J Schilt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  General and comparative endocrinology     Volume:  64     ISSN:  0016-6480     ISO Abbreviation:  Gen. Comp. Endocrinol.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1987-05-06     Completed Date:  1987-05-06     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370735     Medline TA:  Gen Comp Endocrinol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  267-72     Citation Subset:  IM    
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MeSH Terms
Immunoenzyme Techniques
Nervous System / metabolism
Planarians / physiology*
Somatostatin / metabolism*
Turbellaria / physiology*
Reg. No./Substance:

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