| Somatostatin in the treatment of patients with extra-pyramidal disorders and patients with EEG abnormalities. | |
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MedLine Citation:
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PMID: 151476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The growth hormone release inhibiting hormone acts probably both as a true hypophysiotropic hormone and as a neuroregulatory substance. Neurophysiological studies have shown that somatostatin is a CNS depressant. Somatostatin might therefore be of therapeutic significance in neurological diseases. Sixteen patients with different extrapyramidal disorders and seven patients with various EEG abnormalities were tested with 2-hour somatostatin infusions and control infusions with saline. Somatostatin did not induce any improvement or deterioration of symptoms, signs, or EEG abnormalities in any patient. |
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Authors:
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E Dupont; A P Hansen; P Juul-Jensen; K Lundbaek; I Magnussen; B de Fine Olivarius |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Acta neurologica Scandinavica Volume: 57 ISSN: 0001-6314 ISO Abbreviation: Acta Neurol. Scand. Publication Date: 1978 Jun |
Date Detail:
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Created Date: 1978-11-29 Completed Date: 1978-11-29 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370336 Medline TA: Acta Neurol Scand Country: DENMARK |
Other Details:
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Languages: eng Pagination: 488-93 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Basal Ganglia Diseases / drug therapy* Brain Neoplasms / complications Clinical Trials as Topic Double-Blind Method Drug Evaluation Dystonia Musculorum Deformans / drug therapy Epilepsy / drug therapy* Female Humans Huntington Disease / drug therapy Male Middle Aged Myoclonus / drug therapy Parkinson Disease / drug therapy Somatostatin / therapeutic use* Vascular Headaches / drug therapy |
| Chemical | |
Reg. No./Substance:
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51110-01-1/Somatostatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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