Document Detail

Somatostatin in gastric juice in normal subjects and patients with duodenal ulcer.
MedLine Citation:
PMID:  1352198     Owner:  NLM     Status:  MEDLINE    
Somatostatin in gastric juice was determined in normal subjects and patients with duodenal ulcer. Gel exclusion chromatography of gastric juice revealed that the main immunoreactivity existed at the position of somatostatin-14. A large amount of somatostatin was present in gastric juice, and the quantity increased following tetragastrin stimulation. Furthermore, there was a good inverse correlation between somatostatin concentration and acidity of gastric juice; however, there was no difference between normal subjects and patients with duodenal ulcer in the amount of somatostatin released into gastric juice.
K Sumii; M Sumioka; M Yoshihara; A Tari; K Haruma; G Kajiyama
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  37     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-08-06     Completed Date:  1992-08-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1020-4     Citation Subset:  AIM; IM    
First Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
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MeSH Terms
Chromatography, Gel
Duodenal Ulcer / metabolism*
Gastric Acid / secretion
Gastric Acidity Determination
Gastric Juice / chemistry*
Somatostatin / analysis*,  physiology
Tetragastrin / diagnostic use
Reg. No./Substance:
1947-37-1/Tetragastrin; 51110-01-1/Somatostatin

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