| Somatostatin effect on the level of adenyl nucleotides in the blood and tissues of rats during short-lasting hypothermia. | |
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MedLine Citation:
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PMID: 6145295 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Short-lasting hypothermia during thiobutabarbital general anaesthesia causes no decrease of the absolute ATP level in the blood and liver of rats. The adenylate energy charge in the tissues is relatively high - 0.86 in the liver and 0.85 in the muscles, which might be an evidence of a significant "energy sparing" during moderate hypothermia (26 +/- 1 degree C). Somatostatin in a dose of 20 micrograms/kg of body weight given to the rats during hypothermia decreased the ATP level, the ATP/ADP ratio and the adenylate energy charge in the studied tissues, especially in the liver, evidencing increased intensity of catabolic processes caused by the inhibitory action of somatostatin on the release of insulin and glucagon, among other hormones, and on the change of the insulin/glucagon ratio. |
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Authors:
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H Krauss; T Torlińska; J Paluszak; D Kruk; J Koźlik |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta physiologica Polonica Volume: 34 ISSN: 0044-6033 ISO Abbreviation: Acta Physiol Pol Publication Date: 1983 Jul-Aug |
Date Detail:
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Created Date: 1984-07-18 Completed Date: 1984-07-18 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2985166R Medline TA: Acta Physiol Pol Country: POLAND |
Other Details:
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Languages: eng Pagination: 437-44 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Diphosphate
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antagonists & inhibitors,
metabolism* Adenosine Monophosphate / metabolism* Adenosine Triphosphate / antagonists & inhibitors, metabolism* Animals Depression, Chemical Hormones / administration & dosage Hypothermia, Induced* Injections, Intraperitoneal Liver / metabolism Male Muscles / metabolism Rats Rats, Inbred Strains Somatostatin / administration & dosage* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Hormones; 51110-01-1/Somatostatin; 56-65-5/Adenosine Triphosphate; 58-64-0/Adenosine Diphosphate; 61-19-8/Adenosine Monophosphate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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