| Somatosensory evoked potentials in very preterm infants. | |
| | |
MedLine Citation:
|
PMID: 10802462 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Cross-sectional and longitudinal reference values of cortical N(1) peak latency of the median nerve SEP in very preterm infants. METHODS: In infants in a placebo control group within an L-thyroxine supplementation trial, born at less than 30 weeks' gestation, cortical N(1) peak latency was measured at 2 weeks, at term and at 6 months corrected age. Cross-sectional N(1) latency values obtained in 50 infants and complete series of longitudinal values obtained in 15 infants were analyzed in relation to postmenstrual age (PMA). RESULTS: Mean N(1) latency decreased from 66 ms at 2 weeks to 38 ms at term and 20 ms at 6 months corrected age. Possible confounding factors did not have any significant effect on N(1) latency at 2 weeks or at term age except cranial ultrasound abnormalities at 2 weeks of age. CONCLUSIONS: Longitudinal N(1) latency values were consistent with cross-sectional N(1) latency values. The observed N(1) latency at term and at 6 months corrected age suggest that extrauterine maturation of the somatosensory pathway in infants born at less than 30 weeks' gestation is delayed by extrauterine life. |
| | |
Authors:
|
B J Smit; B W Ongerboer de Visser; L S de Vries; F W Dekker; J H Kok |
Publication Detail:
|
Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 111 ISSN: 1388-2457 ISO Abbreviation: Clin Neurophysiol Publication Date: 2000 May |
Date Detail:
|
Created Date: 2000-07-14 Completed Date: 2000-07-14 Revised Date: 2008-09-10 |
Medline Journal Info:
|
Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 901-8 Citation Subset: IM |
Affiliation:
|
Department of Neonatology, Emma Children's Hospital Academic Medical Center, University of Amsterdam, H3N-148, P.O. Box 22700, 1100 DE, Amsterdam, The Netherlands. b.j.smit@amc.uva.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cross-Sectional Studies Evoked Potentials, Somatosensory / drug effects, physiology* Female Gestational Age Humans Infant, Newborn Infant, Premature / physiology* Longitudinal Studies Male Median Nerve / physiology* Placebos Reaction Time Reference Values Thyroxine / therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Placebos; 7488-70-2/Thyroxine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Characteristics of the human contra- versus ipsilateral SII cortex.
Next Document: Alpha burst activity during human REM sleep: descriptive study and functional hypotheses.