Document Detail

Somatosensory evoked potentials in motor neuron disease.
MedLine Citation:
PMID:  4047088     Owner:  NLM     Status:  MEDLINE    
We studied median somatosensory evoked potentials (SEPs) in an unselected series of 30 patients with sporadic motor neuron disease (MND). SEPs were affected in 17 patients (57%), with a higher incidence of abnormality in amyotrophic lateral sclerosis and bulbar palsy than in progressive muscular atrophy. In a majority of patients, simultaneous bilateral stimulation of the median nerve revealed a delay or absence of scalp-recorded central N32 and/or N60, leaving the earlier peaks intact. In the remaining cases, the N19 peak was asymmetrically prolonged. These findings suggest common involvement of somatosensory pathways in MND, either at cortical or subcortical levels, and correlate with neuropathologic reports of neuronal degeneration beyond the primary motor system.
E P Bosch; T Yamada; J Kimura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  8     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1985-11-06     Completed Date:  1985-11-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  556-62     Citation Subset:  IM    
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MeSH Terms
Amyotrophic Lateral Sclerosis / physiopathology
Brain Stem
Evoked Potentials, Somatosensory*
Middle Aged
Motor Neurons*
Muscular Atrophy / physiopathology
Nervous System / physiopathology*
Neural Conduction
Neuromuscular Diseases / physiopathology*
Paralysis / physiopathology
Reaction Time / physiology

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