| Somatosensory evoked potentials are of additional prognostic value in certain patterns of brain injury in term birth asphyxia. | |
| | |
MedLine Citation:
|
PMID: 22264394 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVE: (a) To relate MRI patterns of brain injury to somatosensory evoked potentials (SEPs), and (b) to determine the prognostic value of SEPs in addition to continuous EEG monitoring (cEEG) and cerebral imaging, in term asphyxiated newborns. METHODS: Fifty one consecutive neonates were studied. Survivors were followed for at least 2years. cEEG, started within 24h, was done for ⩾24h and scored. SEPs and MRIs were performed in the first week. Brain injury patterns were classified. RESULTS: Bilaterally abnormal SEPs had a sensitivity of 90% (28/31) and specificity of 85% (17/20) in predicting a poor outcome, defined as death or severe handicap. SEPs were of particular value in predicting outcome in isolated symmetrical white matter injury and predicting the development of hemiparesis in isolated asymmetrical watershed injury. Binary logistic regression analysis revealed a significant relation to outcome separately for cEEG, deep grey matter injury on MRI and SEPs. SEPs provided additional value when added to cEEG and MRI in the model (p=0.034). CONCLUSIONS: SEPs are of additional prognostic value after term birth asphyxia. SIGNIFICANCE: In certain patterns of postasphyxial neonatal brain injury like asymmetrical watershed lesions and symmetrical white matter injury, EPs are complementary to information obtained from cEEG and MRI for prognostication. |
| | |
Authors:
|
Renate M C Swarte; Perumpillichira J Cherian; Maarten Lequin; Gerhard H Visser; Paul Govaert |
Related Documents
:
|
21569474 - Feasibility of magnetic bead technology for concentration of mycobacteria in sputum pri... 9887594 - Use of magnetic resonance in body composition studies: applications to research on calo... 19021824 - Carotid body tumors: advantages of contrast ultrasound investigation. 21178034 - Mri of the knee joint in asymptomatic adolescent soccer players: a controlled study. 15538144 - Origin of high signal intensity in the cavernous sinus in mr angiographic source images... 21885514 - Synovitis and osteitis are very frequent in rheumatoid arthritis clinical remission: re... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-18 |
Journal Detail:
|
Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: - ISSN: 1872-8952 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Neonatology, Erasmus MC-Sophia, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bone marrow mononuclear cells and acute myocardial infarction.
Next Document: Clinical Measures of Prospective Memory in Amnestic Mild Cognitive Impairment.