Document Detail


Somatosensory auras in focal epilepsy: a clinical, video EEG and MRI study.
MedLine Citation:
PMID:  15911361     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine the clinical characteristics of somatosensory auras (SSA) and analyse features of seizure semiology predictive for localization in focal neocortical and limbic epilepsy. METHODS: This study analyses the clinical, video-EEG and MRI imaging features of 75 consecutive patients with focal epilepsy who described somatosensory auras at seizure onset to determine the frequency and localising value of SSAs in different types of focal epilepsy. Sensory characteristics, somatotopic distribution, evolution of the auras and subsequent ictal features in relation to MRI and EEG findings were analysed. RESULTS: The incidence of SSAs in 600 patients with focal epilepsy was 12%. Seventy-five patients were studied further: 77% reported tingling. Pain, thermal changes and a sense of movement or pulling were also reported. Distal unilateral auras in the hand and arm (46%) were most frequent and associated with a contralateral centroparietal focus. Contralateral auras were reported in 62% of lesional cases, focal cortical dysplasia was the commonest pathology in operated cases. Bilateral auras were associated with more diffuse pathologies or parasagittal foci. Evolution was centrifugal, somatotopic and usually unilaterally confined. Subsequent motor semiology was postural tonic, unilateral clonic, psychomotor or secondary generalized. CONCLUSION: SSA are highly correlated with centroparietal epilepsy but may occur in temporal lobe, mesial frontal and multifocal epilepsy. A lesional etiology including discrete dysplasias, tumours, ischemic and postencephalitic gliosis is likely.
Authors:
I E B Tuxhorn
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Seizure : the journal of the British Epilepsy Association     Volume:  14     ISSN:  1059-1311     ISO Abbreviation:  Seizure     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-24     Completed Date:  2005-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9306979     Medline TA:  Seizure     Country:  England    
Other Details:
Languages:  eng     Pagination:  262-8     Citation Subset:  IM    
Affiliation:
Section of Epilepsy Surgery, Epilepsy Center Bethel, Maraweg 21, 33617 Bielefeld, Germany. tux@mara.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cerebral Cortex / pathology,  physiopathology
Child
Electroencephalography / methods*
Epilepsies, Partial / complications,  pathology,  physiopathology*
Female
Functional Laterality
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Seizures / complications,  pathology,  physiopathology*
Video Recording

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