| Somatic cell hybrids between totipotent mouse teratocarcinoma and rat hepatoma cells. | |
| | |
MedLine Citation:
|
PMID: 44296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We have produced somatic cell hybrids between totipotent mouse teratocarcinoma cells and rat hepatoma cells. These hybrids were tested for the expression of liver specific functions expressed in the hepatoma cell parent and for their ability to differentiate when injected into nude mice. The results of this study indicate that hybrid cell clones do not resemble either of the parental cells, since they do not produce albumin and tyrosine aminotransferase that are expressed in the rat hepatoma parent, and are incapable of forming either teratocarcinomas or hepatomas when injected in experimental animals. |
| | |
Authors:
|
G Litwack; C M Croce |
Related Documents
:
|
1309666 - Formation and ultrastructure of somatic cell hybrids. 2590196 - The autoinhibitor of cell fusion in dictyostelium inhibits calmodulin. 15345126 - Culture and expansion of the human embryonic stem cell line hs181, evaluated in a doubl... 20724526 - Incomplete reprogramming after fusion of human multipotent stromal cells and bronchial ... 12200256 - Evolution of fast development of planktonic embryos to early swimming. 17522206 - Chicken heat shock protein 90 is a component of the putative cellular receptor complex ... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Journal of cellular physiology Volume: 101 ISSN: 0021-9541 ISO Abbreviation: J. Cell. Physiol. Publication Date: 1979 Oct |
Date Detail:
|
Created Date: 1980-06-16 Completed Date: 1980-06-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0050222 Medline TA: J Cell Physiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Albumins
/
biosynthesis Animals Cell Differentiation Cell Line Chromosomes / analysis Hybrid Cells / cytology*, metabolism, ultrastructure Isoenzymes / biosynthesis Liver Neoplasms, Experimental / pathology* Mice Mice, Nude Neoplasm Proteins / biosynthesis Neoplasm Transplantation Neoplasms, Experimental / pathology Rats Receptors, Glucocorticoid / metabolism Teratoma / pathology* Tyrosine Transaminase / biosynthesis |
| Chemical | |
Reg. No./Substance:
|
0/Albumins; 0/Isoenzymes; 0/Neoplasm Proteins; 0/Receptors, Glucocorticoid; EC 2.6.1.5/Tyrosine Transaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Further studies on microbiological ring-expansion of penicillin N.
Next Document: Effect of cell density on energy-dependent calcium uptake by Balb/c 3T3 membranes is independent of ...