Document Detail


Somatic antigens of Shigella: structure of the O-specific polysaccharide chain of the Shigella dysenteriae type 7 lipopolysaccharide.
MedLine Citation:
PMID:  2463086     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
4-(N-Acetylglycyl)amino-4,6-dideoxy-D-glucose has been identified as a component of the Shigella dysenteriae type 7 O-specific polysaccharide, in addition to the previously reported 2-acetamido-2-deoxy-D-glucose and 2-acetamido-2-deoxy-D-galacturonic acid. On the basis of selective cleavage with anhydrous hydrogen fluoride and analysis by 1H- and 13C-n.m.r. spectroscopy and f.a.b.-mass spectrometry, it was concluded that the tetrasaccharide repeating-unit of the polysaccharide has the following structure: (structure; see text) where D-GalNAcAN is 2-acetamido-2-deoxy-D-galacturonamide and D-Qui4N is 4-amino-4,6-dideoxy-D-glucose.
Authors:
Y A Knirel; V V Dashunin; A S Shashkov; N K Kochetkov; B A Dmitriev; I L Hofman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Carbohydrate research     Volume:  179     ISSN:  0008-6215     ISO Abbreviation:  Carbohydr. Res.     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1989-02-10     Completed Date:  1989-02-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0043535     Medline TA:  Carbohydr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  51-60     Citation Subset:  IM    
Affiliation:
N. D. Zelinsky Institute of Organic Chemistry, Academy of Sciences of the U.S.S.R., Moscow.
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MeSH Terms
Descriptor/Qualifier:
Antigens, Bacterial* / analysis
Carbohydrate Conformation
Carbohydrate Sequence
Carbohydrates / analysis
Chemical Phenomena
Chemistry
Hydrolysis
Lipopolysaccharides* / analysis
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Sequence Data
Molecular Structure
O Antigens
Pseudomonas aeruginosa / immunology
Shigella dysenteriae / immunology*
Chemical
Reg. No./Substance:
0/Antigens, Bacterial; 0/Carbohydrates; 0/Lipopolysaccharides; 0/O Antigens

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