| Somatic angiotensin converting enzyme in varicocele. | |
| | |
MedLine Citation:
|
PMID: 16728350 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The ACE is found as two isozymes in the body. A somatic isozyme found in blood and several other tissues, and a testis-specific isozyme found only in developing spermatids and mature sperm. In this study, we investigated the ACE activity in left spermatic vein blood samples of infertile patients with varicocele and its correlation to spermatologic parameters. The somatic ACE activities were determined in the peripheral and left spermatic vein blood samples from 31 infertile patients who underwent variococelectomy, and 11 fertile control subjects underwent left inguinal herniorraphy. The somatic ACE activity was measured by kinetic spectrophotometric assay. Semen analyses were performed according to WHO guidelines. The mean somatic ACE activities of peripheral and left spermatic veins of the varicocele group were 60.3 +/- 23.0 and 60.2 +/- 23.2 U/L, respectively. In control group, peripheral and left spermatic vein ACE activities were found as 56.8 +/- 17.1 and 56.5 +/- 15.5 U/L, respectively. There was no significant difference between the ACE activity in peripheral and left spermatic vein blood sample from the varicocele and control group. There was no statistically significant correlation between the spermatologic parameters and ACE activities in the spermatic and peripheral vein in both of varicocele and control groups. As a result, it may be suggested that the somatic ACE has no causative role in pathophysiology of varicocele and varicocele related infertility. |
| | |
Authors:
|
R Asci; S Sarikaya; R Buyukalpelli; A Yilmaz; A Bedir |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Archives of andrology Volume: 52 ISSN: 0148-5016 ISO Abbreviation: Arch. Androl. Publication Date: 2006 Jul-Aug |
Date Detail:
|
Created Date: 2006-05-26 Completed Date: 2006-08-10 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7806755 Medline TA: Arch Androl Country: England |
Other Details:
|
Languages: eng Pagination: 329-34 Citation Subset: IM |
Affiliation:
|
Department of Urology, School of Medicine, Ondokuz Mayis University, Samsun, Turkey. rasci@omu.edu.tr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Follicle Stimulating Hormone
/
blood Humans Infertility, Male Luteinizing Hormone / blood Male Peptidyl-Dipeptidase A / metabolism* Prolactin / blood Reference Values Sperm Count Sperm Motility Testis / anatomy & histology, blood supply Testosterone / blood Varicocele / blood, enzymology* |
| Chemical | |
Reg. No./Substance:
|
58-22-0/Testosterone; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone; EC 3.4.15.1/Peptidyl-Dipeptidase A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Inhibin B levels in peripheral vein do not correlate with inhibin B levels in the spermatic vein in ...
Next Document: Manifestation of toxocariasis in children with neuroblastoma treated with autologous hematopoietic t...