| Solving dynamical inverse problems by means of Metabolic P systems. | |
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MedLine Citation:
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PMID: 22261639 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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MP (Metabolic P) systems are a class of P systems introduced for modelling metabolic processes. We refer to the dynamical inverse problem as the problem of identifying (discrete) mathematical models exhibiting an observed dynamics. In this paper, we complete the definition of the algorithm LGSS (Log-gain Stoichiometric Stepwise regression) introduced in Manca and Marchetti (2011) for solving a general class of dynamical inverse problems. To this aim, we develop a reformulation of the classical stepwise regression in the context of MP systems. We conclude with a short review of two applications of LGSS for discovering the internal regulation logic of two phenomena relevant in systems biology. |
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Authors:
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V Manca; L Marchetti |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-12 |
Journal Detail:
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Title: Bio Systems Volume: - ISSN: 1872-8324 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0430773 Medline TA: Biosystems Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Ireland Ltd. |
Affiliation:
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University of Verona, Department of Computer Science, Strada Le Grazie 15, 37134 Verona, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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