Document Detail


Solvent-preserved, bovine cancellous bone blocks used for reconstruction of thoracolumbar fractures in minimally invasive spinal surgery-first clinical results.
MedLine Citation:
PMID:  15248056     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated the osseointegration of solvent-preserved, xenogenous cancellous bone blocks in the treatment of unstable fractures of the thoracolumbar junction. In 22 patients, the anterior repair procedure was performed by thoracoscopy or minimally invasive retroperitoneal surgery. Twenty-two patients had undergone monosegmental anterior fusion and were surveyed prospectively. Solvent-preserved, bovine cancellous bone blocks were used in 11 patients; iliac crest bone graft was used in the others. Follow-up after 12 months included CT scans, which revealed successful osseointegration in eight out of 11 patients who had received autogenous iliac crest bone grafts, while three patients showed a partial integration. There were no graft fragmentations. In patients who had received solvent-preserved, xenogenous cancellous bone blocks, complete osseointegration was achieved at the graft-bone interface in only two out of 11 cases, after 1 year. Partial integration was found in three patients. In view of these results, autogenous iliac crest bone grafts are still the unrivalled standard for defect repair in spinal surgery.
Authors:
Markus Schultheiss; Michael Sarkar; Markus Arand; Michael Kramer; Hans-Joachim Wilke; Lothar Kinzl; Erich Hartwig
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2004-07-10
Journal Detail:
Title:  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society     Volume:  14     ISSN:  0940-6719     ISO Abbreviation:  Eur Spine J     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-10     Completed Date:  2005-07-05     Revised Date:  2013-02-19    
Medline Journal Info:
Nlm Unique ID:  9301980     Medline TA:  Eur Spine J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  192-6     Citation Subset:  IM    
Affiliation:
Department of Trauma, Hand and Reconstructive Surgery, University of Ulm, Steinhövelstrasse 9, 89075, Ulm, Germany. markus.schultheiss@medizin.uni-ulm.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Bone Transplantation*
Cattle
Female
Humans
Ilium
Lumbar Vertebrae / injuries*
Male
Middle Aged
Osseointegration / physiology
Prospective Studies
Retroperitoneal Space
Solvents
Spinal Fractures / surgery*
Surgical Procedures, Minimally Invasive / methods*
Thoracic Vertebrae / injuries*
Thoracoscopy
Tissue Preservation / methods*
Transplantation, Autologous
Transplantation, Heterologous
Chemical
Reg. No./Substance:
0/Solvents
Comments/Corrections

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