Document Detail


Solvent-free reaction of some 1,2-diaza-1,3-butadienes with phosphites: environmentally friendly access to new diazaphospholes and E-hydrazonophosphonates.
MedLine Citation:
PMID:  15876093     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
[structures: see text] The present article describes the reaction between 1,2-diaza-1,3-butadienes and trialkyl phosphites, under an atmosphere of nitrogen and under solvent-free conditions, to give alkyl 3,3-dialkoxy-2H-1,2,3lambda5-diazaphosphole-4-carboxylates that, in turn, are converted into corresponding E-hydrazonophosphonates by treatment with THF:water (95:5). These latter compounds are obtained directly by the reaction of 1,2-diaza-1,3-butadienes with trialkyl phosphites in the presence of air. These compounds are useful for the further preparation of dialkyl (5-methyl-3-oxo-2,3-dihydro-1H-4-pyrazolyl)phosphonates and 2-dialkoxyphosphoryl-1,2,3-thiadiazoles.
Authors:
Orazio A Attanasi; Graziano Baccolini; Carla Boga; Lucia De Crescentini; Paolino Filippone; Fabio Mantellini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  70     ISSN:  0022-3263     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-05-06     Completed Date:  2005-08-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4033-7     Citation Subset:  -    
Affiliation:
Istituto di Chimica Organica, Università degli Studi di Urbino Carlo Bo, Via Sasso 75, 61029 Urbino, Italy.
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