Document Detail

Solvent-Free Synthesis of α-Amino Nitrile-Derived Ureas.
MedLine Citation:
PMID:  23320418     Owner:  NLM     Status:  Publisher    
An efficient and environmentally friendly methodology for the solvent-free synthesis of α-amino nitrile derived ureas from α-amino acid based amino nitriles has been developed. At room temperature no epimerization was observed in the resulting ureas, but under microwave heating, epimerization occurred at the chiral center bearing the cyano group.
Pilar Ventosa-Andrés; Juan A González-Vera; M Teresa García-López; Rosario Herranz
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-15
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Instituto de Química Médica (CSIC) , Juan de la Cierva 3, 28006 Madrid, Spain.
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