| Solvent-Free Synthesis of α-Amino Nitrile-Derived Ureas. | |
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MedLine Citation:
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PMID: 23320418 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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An efficient and environmentally friendly methodology for the solvent-free synthesis of α-amino nitrile derived ureas from α-amino acid based amino nitriles has been developed. At room temperature no epimerization was observed in the resulting ureas, but under microwave heating, epimerization occurred at the chiral center bearing the cyano group. |
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Authors:
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Pilar Ventosa-Andrés; Juan A González-Vera; M Teresa García-López; Rosario Herranz |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-15 |
Journal Detail:
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Title: Organic letters Volume: - ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Instituto de Química Médica (CSIC) , Juan de la Cierva 3, 28006 Madrid, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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