Document Detail


Soluble sunscreens fully protect E. coli from disinfection by electrohydraulic discharges.
MedLine Citation:
PMID:  14620816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We show that the ultraviolet radiation emitted, rather than the thermal/pressure shocks or the chemical species that are generated in these events, is the lethal agent that inactivates Escherichia coli colonies exposed to electrohydraulic discharges, EHD. Disinfection is completely suppressed in the presence of <100 mg L(-1) of 2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disulfonic acid, BP9, a commercial water-soluble sunscreen. Viable bacteria decay by logit kinetics with the number of EHD. The fact that the slopes of the logit plots depend inversely on BP9 concentration, and vanish above approximately 30 mg BP9 L(-1), is direct evidence that E. coli is exclusively sterilized by UV radiation in these experiments. Present LD50 photon doses are about 10(3) times larger than those required from low-power germicidal lamps, indicating that high-intensity radiation is able to further promote into inactive channels the lower excited state(s) of nucleic acids responsible for DNA damage. The present study confirms the existence of a significant trade-off between photon efficiency and radiative power in bacterial disinfection by UV light.
Authors:
W K Ching; A J Colussi; M R Hoffmann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Environmental science & technology     Volume:  37     ISSN:  0013-936X     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-11-17     Completed Date:  2004-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4901-4     Citation Subset:  IM    
Affiliation:
W. M. Keck Laboratories, California Institute of Technology, Pasadena, California 91125, USA.
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MeSH Terms
Descriptor/Qualifier:
Benzophenones / chemistry*
Disinfection / methods
Electricity
Escherichia coli / pathogenicity*
Pressure
Solubility
Sunscreening Agents / chemistry*
Ultraviolet Rays
Water Pollutants
Water Purification / methods*
Chemical
Reg. No./Substance:
0/2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disulfonic acid; 0/Benzophenones; 0/Sunscreening Agents; 0/Water Pollutants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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