| Soluble intercellular adhesion molecule 1 (sICAM-1) and malignant melanoma. | |
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MedLine Citation:
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PMID: 8104685 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A soluble form of the intercellular adhesion molecule-1 (sICAM-1) has been reported to be elevated in malignant melanoma. We have studied the expression of sICAM-1 by ELISAs in a series of 85 consecutive sera derived from patients with primary or metastatic melanomas in comparison with control patients and patients with diffuse acute eczema and psoriasis. Our results showed elevated sICAM-1 concentrations in patients with malignant melanoma but also in patients with extensive inflammatory dermatoses. The diagnostic potential of sICAM-1 in malignant melanoma appears to be limited. Further studies are needed to determine whether increased values of sICAM-1 in primary melanomas may predict a progression of the disease. |
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Authors:
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J Viac; A Gueniche; M Faure; A Claudy |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cancer letters Volume: 72 ISSN: 0304-3835 ISO Abbreviation: Cancer Lett. Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-10-29 Completed Date: 1993-10-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600053 Medline TA: Cancer Lett Country: IRELAND |
Other Details:
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Languages: eng Pagination: 191-4 Citation Subset: IM |
Affiliation:
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Clinique Dermatologique, Hôpital E. Herriot, Lyon, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cell Adhesion Molecules / blood* Eczema / blood Enzyme-Linked Immunosorbent Assay Female Humans Intercellular Adhesion Molecule-1 Male Melanoma / blood*, pathology Middle Aged Neoplasm Metastasis Psoriasis / blood Tumor Markers, Biological / blood* |
| Chemical | |
Reg. No./Substance:
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0/Cell Adhesion Molecules; 0/Tumor Markers, Biological; 126547-89-5/Intercellular Adhesion Molecule-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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