Document Detail

Soluble intercellular adhesion molecule 1 (sICAM-1) and malignant melanoma.
MedLine Citation:
PMID:  8104685     Owner:  NLM     Status:  MEDLINE    
A soluble form of the intercellular adhesion molecule-1 (sICAM-1) has been reported to be elevated in malignant melanoma. We have studied the expression of sICAM-1 by ELISAs in a series of 85 consecutive sera derived from patients with primary or metastatic melanomas in comparison with control patients and patients with diffuse acute eczema and psoriasis. Our results showed elevated sICAM-1 concentrations in patients with malignant melanoma but also in patients with extensive inflammatory dermatoses. The diagnostic potential of sICAM-1 in malignant melanoma appears to be limited. Further studies are needed to determine whether increased values of sICAM-1 in primary melanomas may predict a progression of the disease.
J Viac; A Gueniche; M Faure; A Claudy
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer letters     Volume:  72     ISSN:  0304-3835     ISO Abbreviation:  Cancer Lett.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-10-29     Completed Date:  1993-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600053     Medline TA:  Cancer Lett     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  191-4     Citation Subset:  IM    
Clinique Dermatologique, Hôpital E. Herriot, Lyon, France.
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MeSH Terms
Aged, 80 and over
Cell Adhesion Molecules / blood*
Eczema / blood
Enzyme-Linked Immunosorbent Assay
Intercellular Adhesion Molecule-1
Melanoma / blood*,  pathology
Middle Aged
Neoplasm Metastasis
Psoriasis / blood
Tumor Markers, Biological / blood*
Reg. No./Substance:
0/Cell Adhesion Molecules; 0/Tumor Markers, Biological; 126547-89-5/Intercellular Adhesion Molecule-1

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