| Solubilization of saponins of Bupleuri radix with ginseng saponins: cooperative effect of dammarane saponins. | |
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MedLine Citation:
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PMID: 17265304 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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It has been found that the water solubilities of saikosaponins, the active principles of Bupleuri radix, are greatly increased in the presence of ginsenoside-Ro, the glucuronide bisdesmoside of oleanolic acid of Ginseng. No solubilizing effect was observed with the neutral dammarane Saponins of Ginseng. However, the solubilizing effect of ginsenoside-Ro was significantly potentiated in the presence of the dammarane saponins of 20 ( S)-protopanaxadiol. The relationship between the solubilizing effect and the structure of ginsenoside-Ro was also investigated, elucidating the important role of the glucuronide moiety. |
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Authors:
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K Watanabe; H Fujino; T Morita; R Kasai; O Tanaka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Planta medica Volume: 54 ISSN: 0032-0943 ISO Abbreviation: Planta Med. Publication Date: 1988 Oct |
Date Detail:
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Created Date: 2007-01-31 Completed Date: 2009-11-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0066751 Medline TA: Planta Med Country: Germany |
Other Details:
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Languages: eng Pagination: 405-9 Citation Subset: - |
Affiliation:
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Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine, Kasumi, Minami-ku, Hiroshima Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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