| Solubilization of phosphatidylcholine vesicles by hydrophobically modified poly(acrylamide)-co-(acrylic acid): effects of acrylic acid fraction and polymer concentration. | |
| | |
MedLine Citation:
|
PMID: 17685646 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The interaction of hydrophobically modified copolymers of acrylamide and acrylic acid, designated as PAM-C12-AA (X%) (X% indicates the percentage of acrylic acid unit and X = 5, 10, 20), with dimyristoylphosphatidylcholine (DMPC) vesicles has been studied. Complementary techniques including isothermal titration microcalorimetry (ITC), differential scanning calorimetry (DSC), turbidity measurement, calcein leakage measurement, dynamic light scattering (DLS), and transmission electron microscopy (TEM) were used to get comprehensive information. The results show that PAM-C12-AA leads to solubilization of DMPC vesicles. There is a critical concentration (C(s)) for PAM-C12-AA to induce obvious vesicle disruption. This concentration is very close to the critical aggregation concentration (CAC) for the polymer self-aggregation. The Cs values are found to be similar for the three polymers. However, the disruption of DMPC vesicles induced by the polymers increases to a greater degree at higher AA fraction, owing to the increasing strength of interaction between the polymer and the lipid bilayer. |
| | |
Authors:
|
Yanru Fan; Yuchun Han; Yilin Wang |
Related Documents
:
|
19093646 - Enamel deproteinization and its effect on acid etching: an in vitro study. 2095316 - In vitro demineralization of enamel by orange juice, apple juice, pepsi cola and diet p... 2072316 - Determination of the accuracy of three die systems. 17309286 - Particulation of hyperbranched aromatic biopolyesters self-organized by solvent transfo... 5124536 - Lipogenesis from glucose-2- 14 c and acetate-1- 14 c in aorta. 17017786 - Catalytic asymmetric reductive amination of aldehydes via dynamic kinetic resolution. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-08-09 |
Journal Detail:
|
Title: The journal of physical chemistry. B Volume: 111 ISSN: 1520-6106 ISO Abbreviation: J Phys Chem B Publication Date: 2007 Aug |
Date Detail:
|
Created Date: 2007-08-23 Completed Date: 2007-11-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101157530 Medline TA: J Phys Chem B Country: United States |
Other Details:
|
Languages: eng Pagination: 10123-9 Citation Subset: IM |
Affiliation:
|
Key Laboratory of Colloid and Interface Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, People's Republic of China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acrylamides
/
chemistry* Acrylates / chemistry Calorimetry, Differential Scanning Dimyristoylphosphatidylcholine / chemistry* Fluoresceins / chemistry Hydrophobicity Lipid Bilayers / chemistry* Microscopy, Electron, Transmission Permeability Polymers / chemistry Scattering, Radiation Solubility Unilamellar Liposomes / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Acrylamides; 0/Acrylates; 0/Fluoresceins; 0/Lipid Bilayers; 0/Polymers; 0/Unilamellar Liposomes; 0/poly(acrylamide-co-acrylic acid); 13699-48-4/Dimyristoylphosphatidylcholine; 1461-15-0/fluorexon; 79-10-7/acrylic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Water-Nafion equilibria. absence of Schroeder's paradox.
Next Document: Thermodynamic characterization of polyanetholesulfonic acid and its alkaline salts.