| Solitary spinal metastasis of Hürthle cell thyroid carcinoma. | |
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MedLine Citation:
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PMID: 20359896 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hürthle cell carcinoma is a rare variant of differentiated thyroid cancer that occasionally forms distant metastases. However, even in the presence of metastases, patients with Hürthle cell carcinoma have a relatively good prognosis. There are few reports of Hürthle cell carcinoma metastases to the vertebral column, and none describing aggressive resection of spinal metastases. Here, we report a 68-year-old woman with a solitary metastasis of Hürthle cell carcinoma to the T1 vertebral body causing severe kyphotic deformity, myelopathy, and pain. The patient was treated with aggressive excisional decompression of the spinal cord and T1 vertebral body resection from an entirely posterior approach. Reconstruction and stabilization of the anterior spine was accomplished with a transforaminal lumbar interbody fusion allograft spacer and posterior instrumentation. We discuss aspects of the diagnosis, management, patient selection, and surgical treatment of metastatic Hürthle cell carcinoma in reference to the literature. |
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Authors:
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Daniel M Sciubba; Rory J Petteys; Steven Kang; Khoi D Than; Ziya L Gokaslan; Gary L Gallia; Jean-Paul Wolinsky |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-04-01 |
Journal Detail:
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Title: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Volume: 17 ISSN: 1532-2653 ISO Abbreviation: J Clin Neurosci Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-03 Completed Date: 2010-08-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9433352 Medline TA: J Clin Neurosci Country: Scotland |
Other Details:
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Languages: eng Pagination: 797-801 Citation Subset: IM |
Copyright Information:
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Copyright 2009. Published by Elsevier Ltd. |
Affiliation:
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Department of Neurosurgery, Johns Hopkins University, 600 N. Wolfe Street, Meyer 8-161, Baltimore, MD 21287, USA. dsciubb1@jhmi.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carcinoma / pathology* Female Humans Magnetic Resonance Imaging / methods Obesity Spinal Neoplasms / pathology, secondary*, surgery Thyroid Neoplasms / pathology* Tomography, X-Ray Computed / methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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