| Solitary pulmonary nodules: a comparative study evaluated with contrast-enhanced dynamic MR imaging and CT. | |
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MedLine Citation:
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PMID: 15538149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this prospective study was to compare the diagnostic performances of dynamic MR imaging and CT for the differentiation of benign and malignant solitary pulmonary nodules (SPNs). METHODS: Eighty-one patients with SPNs (32 malignant, 49 benign) underwent dynamic MR imaging (n=31), dynamic CT (n=27), or both (n=23). The degree of peak enhancement of benign and malignant SPNs was compared on both dynamic MR imaging and CT. Receiver operating characteristic (ROC) analysis was performed to compare the diagnostic performances of dynamic MR imaging and CT. RESULTS: The malignant SPNs revealed significantly greater degrees of peak enhancement on dynamic MR imaging (mean +/- SD [p%SI] 131.2 +/- 46.1 versus 54.2 +/- 45.3; range [p%SI] 82.6-260.0 versus -0.7-171.7; P <0.0001) and CT (mean +/- SD [DMI] 37.8 +/- 15.1 versus 17.9 +/- 21.8; range [DMI] 14.1-68.2 versus -5.4-107.6; P=0.0004). Although dynamic MR imaging was somewhat superior to dynamic CT, the diagnostic performances of the 2 modalities based on ROC analysis were not statistically significant. CONCLUSIONS: Dynamic MR imaging and CT seem to be equally well suited for the differentiation between benign and malignant SPNs. |
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Authors:
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Jeong Ho Kim; Hyung-Jin Kim; Kyung-Hee Lee; Kwang Ho Kim; Hong Lyeol Lee |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 28 ISSN: 0363-8715 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2004 Nov-Dec |
Date Detail:
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Created Date: 2004-11-11 Completed Date: 2004-12-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 766-75 Citation Subset: IM |
Affiliation:
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Department of Radiology, Inha University Hospital, Incheon, Republic of Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Contrast Media* Female Gadolinium DTPA / diagnostic use Humans Image Enhancement / methods Image Processing, Computer-Assisted Iohexol / diagnostic use Lung Neoplasms / diagnosis*, radiography Magnetic Resonance Imaging / methods*, statistics & numerical data Male Middle Aged Predictive Value of Tests Prospective Studies ROC Curve Radiographic Image Enhancement / methods Sensitivity and Specificity Solitary Pulmonary Nodule / diagnosis*, radiography Tomography, Spiral Computed* / statistics & numerical data |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 66108-95-0/Iohexol; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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