Document Detail

Solitary hepatic lymphangioma: report of a case.
MedLine Citation:
PMID:  20740355     Owner:  NLM     Status:  MEDLINE    
A 52-year-old woman presented with upper abdominal pain. Abdominal ultrasonography showed a 4-cm well-defined mass containing solid and cystic components in segment IV of the liver, and contrast-enhanced T1-weighted magnetic resonance imaging revealed heterogeneous enhancement within the tumor, indicating a solid or fibrous component. There were no cystic lesions in any other organs. A partial hepatectomy was performed, based on a preoperative diagnosis of sclerosing hemangioma and biliary cystadenoma or cystadenocarcinoma. Pathologically, the tumor appeared to be a multilocular and cystic lesion lined by attenuated endothelial- like cells with no atypia. Immunohistochemistry demonstrated the endothelial-like cells to be positive for the lymphatic-specific markers D2-40, LYVE-1, and Prox-1, which proved helpful for confirming the diagnosis as solitary hepatic lymphangioma. This case is presented with details of the pathologic and radiologic findings, because solitary hepatic lymphangioma is an extremely rare tumor and no previous reports have provided details of the immunohistochemical characteristics.
Takuya Matsumoto; Hidenori Ojima; Yuri Akishima-Fukasawa; Nobuyoshi Hiraoka; Hiroaki Onaya; Kazuaki Shimada; Yasunori Mizuguchi; Shintaro Sakurai; Toshiharu Ishii; Tomoo Kosuge; Yae Kanai
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-08-26
Journal Detail:
Title:  Surgery today     Volume:  40     ISSN:  1436-2813     ISO Abbreviation:  Surg. Today     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-26     Completed Date:  2011-01-19     Revised Date:  2012-03-02    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  883-9     Citation Subset:  IM    
Pathology Division, National Cancer Center Hospital, Tokyo, Japan.
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MeSH Terms
Antibodies, Monoclonal / diagnostic use
Antibodies, Monoclonal, Murine-Derived
Homeodomain Proteins / analysis
Liver Neoplasms / chemistry,  diagnosis*,  surgery
Lymphangioma / chemistry,  diagnosis*,  surgery
Middle Aged
Tumor Suppressor Proteins / analysis
Vesicular Transport Proteins / analysis
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Antibodies, Monoclonal, Murine-Derived; 0/Homeodomain Proteins; 0/LYVE1 protein, human; 0/Tumor Suppressor Proteins; 0/Vesicular Transport Proteins; 0/monoclonal antibody D2-40; 0/prospero-related homeobox 1 protein

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