Document Detail

Solitary fibrous tumor of the oral cavity: an uncommon location for a ubiquitous neoplasm.
MedLine Citation:
PMID:  10348518     Owner:  NLM     Status:  MEDLINE    
Solitary fibrous tumor is an uncommon soft tissue tumor initially reported in the pleura but recently described in other sites of the body. To date, only 5 examples of oral solitary fibrous tumor have been reported. Here, we describe 2 additional cases of this tumor in the oral cavity. The tumors were composed of small to medium-sized spindle cells with bland cytologic features; these cells were haphazardly arranged in highly cellular sheets or ill-formed fascicles as well as in hypocellular areas with hyalinized blood vessels. Both tumors contained blood vessels with a hemangiopericytomalike appearance and expressed vimentin, CD34, and CD99. One case was also strongly positive for bcl-2. The diagnosis of solitary fibrous tumor may be difficult inasmuch as it shares a number of histologic features with other soft tissue tumors. Awareness of its occurrence in the oral cavity is important so that confusion with other spindle cell neoplasms can be avoided.
B Perez-Ordonez; I G Koutlas; E Strich; R W Gilbert; R C Jordan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  87     ISSN:  1079-2104     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-07-12     Completed Date:  1999-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  589-93     Citation Subset:  D; IM    
Department of Laboratory Medicine, Sunnybrook Health Science Centre, North York, Ontario, Canada.
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MeSH Terms
Diagnosis, Differential
Immunoenzyme Techniques
Mouth Neoplasms / chemistry,  pathology*
Neoplasm Proteins / analysis
Neoplasms, Fibrous Tissue / chemistry,  pathology*
Soft Tissue Neoplasms / chemistry,  pathology*
Vimentin / analysis
Reg. No./Substance:
0/Neoplasm Proteins; 0/Vimentin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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