Document Detail


Solitary fibrous tumor of the oral cavity: an uncommon location for a ubiquitous neoplasm.
MedLine Citation:
PMID:  10348518     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Solitary fibrous tumor is an uncommon soft tissue tumor initially reported in the pleura but recently described in other sites of the body. To date, only 5 examples of oral solitary fibrous tumor have been reported. Here, we describe 2 additional cases of this tumor in the oral cavity. The tumors were composed of small to medium-sized spindle cells with bland cytologic features; these cells were haphazardly arranged in highly cellular sheets or ill-formed fascicles as well as in hypocellular areas with hyalinized blood vessels. Both tumors contained blood vessels with a hemangiopericytomalike appearance and expressed vimentin, CD34, and CD99. One case was also strongly positive for bcl-2. The diagnosis of solitary fibrous tumor may be difficult inasmuch as it shares a number of histologic features with other soft tissue tumors. Awareness of its occurrence in the oral cavity is important so that confusion with other spindle cell neoplasms can be avoided.
Authors:
B Perez-Ordonez; I G Koutlas; E Strich; R W Gilbert; R C Jordan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  87     ISSN:  1079-2104     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-07-12     Completed Date:  1999-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  589-93     Citation Subset:  D; IM    
Affiliation:
Department of Laboratory Medicine, Sunnybrook Health Science Centre, North York, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Diagnosis, Differential
Female
Humans
Immunoenzyme Techniques
Male
Mouth Neoplasms / chemistry,  pathology*
Neoplasm Proteins / analysis
Neoplasms, Fibrous Tissue / chemistry,  pathology*
Soft Tissue Neoplasms / chemistry,  pathology*
Vimentin / analysis
Chemical
Reg. No./Substance:
0/Neoplasm Proteins; 0/Vimentin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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