| Solid food introduction in relation to eczema: results from a four-year prospective birth cohort study. | |
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MedLine Citation:
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PMID: 17889067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the association between the introduction of solid foods in the first 12 months and the occurrence of eczema during the first 4 years of life in a prospective study of newborns. STUDY DESIGN: Data were taken from annually administered questionnaires from a large birth cohort (recruited 1995-1998) comprised of an intervention and a nonintervention group. Outcomes were doctor-diagnosed and symptomatic eczema. Multiple generalized estimation equation models were performed for the 2 study groups. RESULTS: From the 5991 recruited infants, 4753 (79%) were followed up. The 2 study groups were different in their family risk of allergies and feeding practices. No association was found between the time of introduction of solids or the diversity of solids and eczema. In the nonintervention group, a decreased risk was observed for avoidance of soybean/nuts, but an increased risk was seen in doctor-diagnosed eczema for the avoidance of egg in the first year. CONCLUSION: The evidence from this study supports neither a delayed introduction of solids beyond the fourth month nor a delayed introduction of the most potentially allergenic solids beyond the sixth month of life for the prevention of eczema. However, effects under more extreme conditions cannot be ruled out. |
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Authors:
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Birgit Filipiak; Anne Zutavern; Sibylle Koletzko; Andrea von Berg; Inken Brockow; Armin Grübl; Dietrich Berdel; Dietrich Reinhardt; Carl Peter Bauer; H-Erich Wichmann; Joachim Heinrich; |
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Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2007-08-23 |
Journal Detail:
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Title: The Journal of pediatrics Volume: 151 ISSN: 1097-6833 ISO Abbreviation: J. Pediatr. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-09-24 Completed Date: 2007-10-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 352-8 Citation Subset: AIM; IM |
Affiliation:
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GSF-National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Dermatitis, Atopic
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epidemiology,
prevention & control* Diet* Eczema / epidemiology, prevention & control Family Health Female Food Hypersensitivity / prevention & control Germany / epidemiology Humans Infant Infant Food* Infant, Newborn Male Prospective Studies Risk Factors Time Factors |
| Comments/Corrections | |
Comment In:
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J Pediatr. 2007 Oct;151(4):331-3
[PMID:
17889061
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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