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Solanum nigrum: Current Perspectives on Therapeutic Properties.
MedLine Citation:
PMID:  21438649     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Solanum nigrum (black nightshade) is widely used in ethnomedicine for its hepatoprotective, anti-proliferative, anti-inflammatory and anti-oxidative properties. The major active components documented are glycoalkaloids (solamargine, solasonine and solanine), glycoproteins and polysaccharides apart from polyphenols (gallic acid, catechin, protocatechuic acid, caffeic acid, epicatecin, rutin and naringenin). It is mainly used in polyherbal formulations targeting liver diseases problems. Documentation using scientifically validated assay systems shows that S. nigrum can offer new candidate drugs for commercialization. It is also a non-fastidious plant which can grow under limiting nutrient conditions on degraded land. This review discusses its usage in traditional systems of medicine and links them to experimentally proven activities in in vitro and in vivo systems.
Authors:
Ramya Jain; Anjali Sharma; Sanjay Gupta; Indira P Sarethy; Reema Gabrani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Alternative medicine review : a journal of clinical therapeutic     Volume:  16     ISSN:  1089-5159     ISO Abbreviation:  Altern Med Rev     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9705340     Medline TA:  Altern Med Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  78-85     Citation Subset:  K    
Affiliation:
Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, NOIDA, India. Email: reema.gabrani@jiit.ac.in.
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