| Software-based fusion of PET and CT images for suspected recurrent lung cancer. | |
| | |
MedLine Citation:
|
PMID: 18293042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: The purpose of this study was to compare the diagnostic performance of the manual fusion of positron emission tomography (PET) and computed tomography (CT) images with that of CT alone and that of side-by-side PET and CT (PET/CT) in patients with suspected recurrent lung cancer. PROCEDURES: Fifty-three patients who had previously had surgery for lung cancer underwent a whole-body 2-deoxy-2-[F-18]fluoro-D-glucose (FDG)-PET scan, followed by a diagnostic CT scan. The PET and CT images were fused on a workstation. CT alone, PET/CT, and fused images were evaluated separately using a five-point grading scale (0=definitely negative, 1=probably negative, 2=equivocal, 3=probably positive, and 4=definitely positive). Lesions of grade 3 or 4 were considered positive, and diagnostic accuracy and certainty were evaluated. RESULTS: Overall, 67 lesions in 33 patients were considered true positive pathologically or clinically. Of these 67 lesions, the evaluation of CT, PET/CT, and fused images detected 46, 55, and 66 lesions, respectively, with the number of grade 4 lesions detected being 38, 50, and 63, respectively. The diagnostic accuracy of CT, PET/CT, and fused images according to patients was 75%, 79%, and 87%, respectively. CONCLUSION: These results suggest that interpreting fused images increased diagnostic certainty for detecting recurrence and provided more accurate diagnoses. |
| | |
Authors:
|
Yuji Nakamoto; Michio Senda; Tomohisa Okada; Setsu Sakamoto; Tsuneo Saga; Tatsuya Higashi; Kaori Togashi |
Publication Detail:
|
Type: Journal Article Date: 2008-02-22 |
Journal Detail:
|
Title: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Volume: 10 ISSN: 1536-1632 ISO Abbreviation: Mol Imaging Biol Publication Date: 2008 May-Jun |
Date Detail:
|
Created Date: 2008-05-07 Completed Date: 2008-09-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101125610 Medline TA: Mol Imaging Biol Country: United States |
Other Details:
|
Languages: eng Pagination: 147-53 Citation Subset: IM |
Affiliation:
|
Department of Diagnostic Radiology, Kyoto University Hospital, Kyoto, Japan. ynakamo1@kuhp.kyoto-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Female Humans Lung Neoplasms / diagnosis* Male Middle Aged Neoplasm Recurrence, Local / diagnosis* Positron-Emission Tomography / methods* Sensitivity and Specificity Software* Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Potential chemosignals in the anogenital gland secretion of giant pandas, Ailuropoda melanoleuca, as...
Next Document: A stochastic spatial dynamical model for Aedes aegypti.