Document Detail


Soft tissue facial angles in Down's syndrome subjects: a three-dimensional non-invasive study.
MedLine Citation:
PMID:  16043473     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the present study was to obtain quantitative information concerning the three-dimensional (3D) arrangement of the facial soft tissues of subjects with Down's syndrome. The 3D co-ordinates of 50 soft tissue facial landmarks were recorded by an electromechanical digitizer in 17 male and 11 female subjects with Down's syndrome aged 12-45 years, and in 429 healthy individuals of the same age, ethnicity and gender. From the landmark co-ordinates, geometric calculations were obtained of several 3D facial angles: facial convexity in the horizontal plane (upper facial convexity, mid facial convexity including the nose, and lower facial convexity), mandibular corpus convexity in the horizontal plane, facial convexity including the nose, facial convexity excluding the nose, interlabial angle, nasolabial angle, angle of nasal convexity, left and right soft tissue gonial angles. Data were compared with that collected for the normal subjects by computing the z-scores. Facial convexity in the horizontal plane (both in the upper and mid facial third), facial convexity in the sagittal plane and the angle of nasal convexity were significantly (P < 0.05) increased (flatter) in subjects with Down's syndrome than in the normal controls. Both left and right soft tissue gonial angles were significantly reduced (more acute) in the Down's syndrome subjects. Subjects with Down's syndrome had a more hypoplastic facial middle third with reduced nasal protrusion, and a reduced lower facial third (mandible) than reference, normal subjects.
Authors:
Virgilio F Ferrario; Claudia Dellavia; Graziano Serrao; Chiarella Sforza
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of orthodontics     Volume:  27     ISSN:  0141-5387     ISO Abbreviation:  Eur J Orthod     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-26     Completed Date:  2005-12-08     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  7909010     Medline TA:  Eur J Orthod     Country:  England    
Other Details:
Languages:  eng     Pagination:  355-62     Citation Subset:  D; IM    
Affiliation:
Functional Anatomy Research Centre, Laboratorio di Anatomia Funzionale dell'Apparato Stomatognatico, Dipartimento di Morfologia Umana, Facoltà di Medicina e Chirurgia and Facoltà di Scienze Motorie, Università degli Studi di Milano, Italy. farc@unimi.it
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cephalometry
Child
Down Syndrome / pathology*
Esthetics, Dental*
Face / pathology*
Facies*
Female
Humans
Image Processing, Computer-Assisted
Imaging, Three-Dimensional*
Jaw / pathology*
Male
Middle Aged
Models, Anatomic
Vertical Dimension

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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