Document Detail

Soft tissue augmentation with ArteFill.
MedLine Citation:
PMID:  19415579     Owner:  NLM     Status:  MEDLINE    
ArteFill is a novel, third-generation polymethylmethacrylate (PMMA) injectable filler with unique properties. When compared with predecessor materials, ArteFill demonstrates improved biocompatibility as a result of more uniform PMMA microsphere size and shape. This translates into less adverse events after placement. ArteFill can provide a permanent volume enhancement by stimulation of fibroblasts that encapsulate nonabsorbable microspheres with collagen deposition. Currently, ArteFill is FDA approved for permanent augmentation of moderately deep nasolabial folds. It is also commonly used off-label for augmentation of other skin creases and regional areas of volume deficiency, such as the tear trough-malar and marionette line-prejowl sulcus regions. The key to success with ArteFill is a conservative approach with avoidance of overcorrection. Proper technique includes deep dermal to subcutaneous placement with full correction achieved gradually over several treatments. Complications are mostly limited to nodule formation, which is easily managed in most cases with conservative intervention.
John M Hilinski; Steven R Cohen
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Publication Detail:
Type:  Journal Article     Date:  2009-05-04
Journal Detail:
Title:  Facial plastic surgery : FPS     Volume:  25     ISSN:  1098-8793     ISO Abbreviation:  Facial Plast Surg     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-05     Completed Date:  2009-07-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405303     Medline TA:  Facial Plast Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  114-9     Citation Subset:  D    
San Diego Face and Neck Specialties, San Diego, California 92103, USA.
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MeSH Terms
Biocompatible Materials / administration & dosage*
Chondrogenesis / drug effects
Collagen / administration & dosage*
Cosmetic Techniques*
Injections, Subcutaneous / methods
Nose Deformities, Acquired / drug therapy
Patient Selection
Polymethyl Methacrylate / administration & dosage*
Skin Aging
Reg. No./Substance:
0/ArteFill; 0/Biocompatible Materials; 9007-34-5/Collagen; 9011-14-7/Polymethyl Methacrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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