Document Detail

Sodium supplementation in very low birth weight infants fed on their own mothers milk I: Effects on sodium homeostasis.
MedLine Citation:
PMID:  1473517     Owner:  NLM     Status:  MEDLINE    
Sodium supplementation was done on 41 very low birth weight (VLBW) preterm infants with 25 other infants of similar weight status as controls. All the infants were fed on their own mothers milk whose sodium and potassium content was determined. Serum and urinary sodium, potassium and creatinine levels were determined in both groups during the study period of six weeks. Determination of weight gain, length gain and head circumference gain showed that these anthropometric parameters are significantly increased by sodium supplementation while sodium and potassium concentrations were not significantly affected. There were no cases of either hypernatraemia or hyponatraemia though renal excretion of sodium was very high in the supplemented group. Conclusions drawn from the study are that very little weight gain could have been due to fluid retention and that though sodium supplementation does not affect sodium profiles in these infants it has significant effect on their growth rate which may be due to its indirect/direct association with bone and protein metabolism.
R K Ayisi; M J Mbiti; R N Musoke; D A Orinda
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  East African medical journal     Volume:  69     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-02-01     Completed Date:  1993-02-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  591-5     Citation Subset:  IM    
Department of Paediatrics, College of Health Sciences, University of Nairobi, Kenya.
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MeSH Terms
Body Height
Breast Feeding*
Creatinine / blood,  metabolism,  urine
Hospitals, Urban
Infant Food / standards*
Infant Nutritional Physiological Phenomena*
Infant, Low Birth Weight* / blood,  metabolism,  urine
Infant, Newborn
Potassium / blood,  metabolism,  urine
Sodium / blood,  metabolism,  urine
Sodium, Dietary / administration & dosage*
Weight Gain
Reg. No./Substance:
0/Sodium, Dietary; 60-27-5/Creatinine; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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