Document Detail


Sodium intake and hypertension.
MedLine Citation:
PMID:  17046432     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In current diets, the level of sodium is very high, whereas that of potassium, calcium, and magnesium is low compared with the level in diets composed of unprocessed, natural foods. We present the biologic rationale and scientific evidence that show that the current salt intake levels largely explain the high prevalence of hypertension. Comprehensive reduction of salt intake, both alone and particularly in combination with increases in intakes of potassium, calcium, and magnesium, is able to lower average blood pressure levels substantially. During the past 30 years, the one-third decrease in the average salt intake has been accompanied by a more than 10-mm Hg fall in the population average of both systolic and diastolic blood pressure, and a 75% to 80% decrease in both stroke and coronary heart disease mortality in Finland. There is no evidence of any harmful effects of salt reduction. Salt-reduction recommendations alone have a very small, if any, population impact. In the United States, for example, the per capita use of salt increased by approximately 55% from the mid-1980s to the late 1990s. We deal with factors that contribute toward increasing salt intakes and present examples of the methods that have contributed to the successful salt reduction in Finland.
Authors:
Heikki Karppanen; Eero Mervaala
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  49     ISSN:  0033-0620     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-10-18     Completed Date:  2006-11-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59-75     Citation Subset:  AIM; IM    
Affiliation:
Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland. heikki.karppanen@helsinki.fi
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure / drug effects
Humans
Hypertension / etiology*,  metabolism
Risk Factors
Sodium / metabolism
Sodium, Dietary / adverse effects*
Chemical
Reg. No./Substance:
0/Sodium, Dietary; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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