| Sodium sensitivity of blood pressure in Chinese populations. | |
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MedLine Citation:
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PMID: 20424958 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clinical trials have demonstrated that a reduced intake of dietary sodium lowers blood pressure. However, blood pressure reduction in response to a decrease in dietary sodium intake varies considerably among different individuals-a phenomenon described as sodium sensitivity. The Genetic Epidemiology Network of Salt Sensitivity (GenSalt) study was a large family-based dietary-feeding study conducted in rural north China. This study indicated that approximately 39% of Chinese adults were sodium-sensitive. Sodium sensitivity was more common in women and in persons who were older and had higher usual blood pressure. Sodium sensitivity was also more common in individuals with higher responses to a cold pressor test and in individuals with the metabolic syndrome. Genetic factors may play an important role in determining sodium sensitivity in the Chinese population. A better understanding of the genetic and environmental determinants of sodium sensitivity has important public health and clinical implications. |
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Authors:
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Jing Chen |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Current hypertension reports Volume: 12 ISSN: 1534-3111 ISO Abbreviation: Curr. Hypertens. Rep. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2011-06-13 Revised Date: 2011-06-13 |
Medline Journal Info:
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Nlm Unique ID: 100888982 Medline TA: Curr Hypertens Rep Country: United States |
Other Details:
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Languages: eng Pagination: 127-34 Citation Subset: IM |
Affiliation:
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Department of Medicine, Tulane University School of Medicine, SL45, New Orleans, LA 70112, USA. jchen@tulane.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Blood Pressure* China / epidemiology Confidence Intervals Female Geography Humans Hypertension / chemically induced, diet therapy*, epidemiology Life Style Male Metabolic Syndrome X Middle Aged Multivariate Analysis Nutrition Surveys Nutritional Status Odds Ratio Questionnaires Rural Population Sex Factors Sodium Chloride, Dietary / adverse effects, metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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P20-RR017659/RR/NCRR NIH HHS; R01 HL087263-01/HL/NHLBI NIH HHS; R01 HL087263-02/HL/NHLBI NIH HHS; R01 HL087263-02W1/HL/NHLBI NIH HHS; R01 HL087263-03/HL/NHLBI NIH HHS; R01 HL087263-04/HL/NHLBI NIH HHS; R01 HL090682-01A1/HL/NHLBI NIH HHS; R01 HL090682-01A1W1/HL/NHLBI NIH HHS; R01 HL090682-02/HL/NHLBI NIH HHS; R01 HL090682-03/HL/NHLBI NIH HHS; R01HL087263/HL/NHLBI NIH HHS; R01HL090682/HL/NHLBI NIH HHS; U01 HL072507-01/HL/NHLBI NIH HHS; U01 HL072507-02/HL/NHLBI NIH HHS; U01 HL072507-03/HL/NHLBI NIH HHS; U01 HL072507-03S1/HL/NHLBI NIH HHS; U01 HL072507-04/HL/NHLBI NIH HHS; U01 HL072507-04S1/HL/NHLBI NIH HHS; U01 HL072507-05/HL/NHLBI NIH HHS; U01 HL072507-06/HL/NHLBI NIH HHS; U01HL072507/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Sodium Chloride, Dietary |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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