Document Detail


Socially available heroin powders--their chemical compositions and reproductive and behavioural effects on female rats.
MedLine Citation:
PMID:  16414699     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Morphine is one of such substances which produce very intense euphoria and a prolonged period of relaxation and sedation. These opioids are known to cause modifications in neuroendocrine system during different stages of life, ranging from fetal through postnatal to adult. Heroin, an opioid, is a derivative of morphine and its long-term use, both in males and females, is associated with alterations in sexual behaviour and changes in endocrine functions. In females, hormonal imbalance thus resulted, can lead to amenorrhea and in some cases infertility. In Pakistan, heroin is available mixed with different additives in a variety of forms. Two varieties (S1 and S2) procured from patients visiting Drug Rehabilitating Clinic in the Civil Hospital, Karachi, were analysed for their qualitative and quantitative properties.
Authors:
A Siddiqui; A A Zaidi; S Khatoon; C Sultana; V Sultana; Z H Zaidi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pakistan journal of pharmaceutical sciences     Volume:  5     ISSN:  1011-601X     ISO Abbreviation:  Pak J Pharm Sci     Publication Date:  1992 Jan 
Date Detail:
Created Date:  2006-01-17     Completed Date:  2006-03-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426356     Medline TA:  Pak J Pharm Sci     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  13-23     Citation Subset:  -    
Affiliation:
Department of Physiology, The Aga Khan University, Stadium Road, Karachi-74800, Pakistan.
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