Document Detail


Social stress in guinea pigs.
MedLine Citation:
PMID:  2574889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Confrontation studies between eight pairs of two 7-8 months old male guinea pigs, each raised with one female from their 30th day of age, were conducted in an enclosure of 2 m2 in the presence of an unfamiliar female. The opponents were chronically kept together for up to 8 days. When they were not separated after 52 hr, one or (in 1 case) both males fell into a comatose state and died 5-8 days after the onset of the confrontation. Four hr after the onset of the confrontations both opponents showed significantly increased plasma glucocorticoid (CS) titers. At this time as well as 24 hr earlier, prospective winners (PW) and prospective losers (PL) did not yet differ in any physiological parameter measured. Forty-eight hr later, PW were characterized by a low body weight loss, low CS, high testosterone (T) and elevated plasma-catecholamine (CA) values. In contrast, PL showed a high body weight loss, very high CS titers, low T-titers and more elevated CA values than PW. Despite these highly significant differences in physiological parameters, PL and PW did not yet differ in the frequency of any agonistic behavioral element recorded. Seventy-two hr after the onset of the chronic cohabitation, losers began to behave more and more passive, they ceased feeding and drinking and were less and less involved in social interactions. The physiological differences between winners and losers intensified.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
N Sachser; C Lick
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physiology & behavior     Volume:  46     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1990-01-30     Completed Date:  1990-01-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  137-44     Citation Subset:  IM    
Affiliation:
Department of Animal Physiology, University of Bayreuth, West Germany.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Glands / enzymology
Aggression / physiology*
Animals
Behavior, Animal / physiology
Blood Glucose / analysis
Blood Urea Nitrogen
Body Weight
Cholesterol / blood
Creatinine / blood
Dominance-Subordination*
Epinephrine / blood
Glucocorticoids / blood
Guinea Pigs
Male
Norepinephrine / blood
Social Dominance*
Stress, Psychological* / blood,  pathology
Testosterone / blood
Tyrosine 3-Monooxygenase / metabolism
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Glucocorticoids; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 57-88-5/Cholesterol; 58-22-0/Testosterone; 60-27-5/Creatinine; EC 1.14.16.2/Tyrosine 3-Monooxygenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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