Document Detail

Social and physical health risk factors for first-onset major depressive disorder in a community sample.
MedLine Citation:
PMID:  7939965     Owner:  NLM     Status:  MEDLINE    
Using prospective data on 3,170 respondents aged 18 years and over who were at risk for a first-onset major depression from the New Haven site of the Epidemiologic Catchment Area (ECA) study, these analyses assessed the effects of social status, physical health status, and social isolation on first-onset depression in a 1-year period, controlling for demographic characteristics and baseline psychiatric factors. Among the assessed potential risk factors, poverty status [odds ratio (OR = 2.034, P < 0.05)] and confinement to a bed or chair (OR = 4.015, P < 0.05) were independently associated with an increased risk for a first-onset depressive episode when controlling for gender, age, past history of substance abuse, and subclinical depressive symptoms. The effects of poverty, and to a lesser degree homebound status, were substantially reduced when controlling for degree of isolation from friends and family, suggesting that social isolation mediates some of the relationships between social and physical statuses and major depression.
M L Bruce; R A Hoff
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Social psychiatry and psychiatric epidemiology     Volume:  29     ISSN:  0933-7954     ISO Abbreviation:  Soc Psychiatry Psychiatr Epidemiol     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-11-18     Completed Date:  1994-11-18     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8804358     Medline TA:  Soc Psychiatry Psychiatr Epidemiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  165-71     Citation Subset:  IM    
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520-8034.
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MeSH Terms
Age of Onset
Depressive Disorder / psychology*
Health Status
Marital Status
Middle Aged
Prospective Studies
Sex Factors
Social Class
Grant Support

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