| Snoring effects on the baroreflex: An animal model. | |
| | |
MedLine Citation:
|
PMID: 22244879 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Baroreflex sensitivity (BRS) is reduced in humans during snoring, however the mechanisms are unknown. We used an anaesthetised rabbit induced snoring (IS) model, to test: (1) whether IS was associated with reduced BRS; and (2) if snoring related vibration transmission to peri-carotid tissues influenced BRS levels. BRS was quantified using the spontaneous sequence technique. During IS, BRS fell by 40%, without any associated change in blood pressure (BP) but accompanied by an increase in heart rate (HR). Direct application of a snore frequency and intensity matched vibratory stimulus to the peri-carotid tissues of non-snoring tracheostomised rabbits had no effect on BRS, HR or BP. In conclusion, IS induced depression of BRS is likely mediated via a HR driven change in BRS operating point that is unrelated to snoring-related vibration transmission to carotid baroreceptors. The anaesthetised IS rabbit provides a model in which mechanistic interactions between snoring and BRS can be further explored. |
| | |
Authors:
|
Jyotishna Narayan; Jason Amatoury; Jin-Gun Cho; Manisha Verma; Kristina Kairaitis; John Wheatley; Terence C Amis |
Related Documents
:
|
22041839 - Dissecting thoracic aneurysm: an unusual presentation. 22217569 - Arterial stress hormones during scuba diving with different breathing gases. 12047799 - Estimation of baroreflex gain using a baroreflex equilibrium diagram. 21641509 - Pressure ulcers in long-term care. 21715199 - Urodynamic and haemodynamic effects of a single oral administration of ephedrine or phe... 7328919 - Time-dependent changes in open-loop gains of baroreflex systems after massive hemorrhage. 15854849 - The pulse transit time arousal index in obstructive sleep apnea before and after cpap. 6167249 - Distribution of pressure-induced fast axonal transport abnormalities in primate optic n... 20081529 - Leaning during chest compressions impairs cardiac output and left ventricular myocardia... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-6 |
Journal Detail:
|
Title: Respiratory physiology & neurobiology Volume: - ISSN: 1878-1519 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101140022 Medline TA: Respir Physiol Neurobiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012. Published by Elsevier B.V. |
Affiliation:
|
Ludwig Engel Centre for Respiratory Research, Sydney, NSW, Australia; Westmead Millennium Institute, Westmead, Sydney, NSW, Australia; University of Sydney at Westmead Hospital, Westmead, Sydney, NSW, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Management of Minor Head Injury in Patients Receiving Oral Anticoagulant Therapy: A Prospective Stud...
Next Document: Oxygen-glucose deprivation (OGD) and interleukin-1 (IL-1) differentially modulate cathepsin B/L medi...