Document Detail


Snake antivenom product guidelines in India: "the devil is in the details".
MedLine Citation:
PMID:  17896852     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Venomous snakebite continues to exact a tremendous toll in human suffering and mortality in India. Contributing to this problem is the fact that all of the current Indian snake antivenom manufacturers include a great deal of misinformation in the package inserts and guidelines that accompany their products. Examples include erroneous recommendations regarding first aid, misleading information regarding the signs and symptoms to be anticipated after Indian snakebite, and misleading and ambiguous recommendations as to initial dosing and repeat dosing of antivenom. In addition, the significant problem of acute adverse reactions to Indian antivenoms is compounded by a lack of appropriate recommendations regarding prevention, diagnosis, and management of such reactions. It is the intent of this article to point out problems with the current Indian antivenom product guidelines and to encourage these manufacturers to produce new literature to accompany their products based on the best available evidence.
Authors:
Ian D Simpson; Robert L Norris
Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Wilderness & environmental medicine     Volume:  18     ISSN:  1080-6032     ISO Abbreviation:  Wilderness Environ Med     Publication Date:  2007  
Date Detail:
Created Date:  2007-09-27     Completed Date:  2007-11-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505185     Medline TA:  Wilderness Environ Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  163-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antivenins / therapeutic use*
Drug Labeling / standards*
First Aid / standards*
Guidelines as Topic
Humans
India
Snake Bites / diagnosis,  drug therapy*
Snake Venoms / antagonists & inhibitors*
Snakes
Chemical
Reg. No./Substance:
0/Antivenins; 0/Snake Venoms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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