Document Detail

Smoking related to 24-h ambulatory blood pressure and heart rate: a study in 352 normotensive Danish subjects.
MedLine Citation:
PMID:  9160757     Owner:  NLM     Status:  MEDLINE    
This study shows the association between smoking and both office and ambulatory blood pressure. By means of stratification, a uniform number of subjects of both sexes and spanning 6 decades (aged 20 to 79 years) were recruited randomly from the local community register. A total of 352 subjects participated, including 161 smokers. Smokers (both sexes and all age groups summed), as compared with nonsmokers had statistically significant lower office blood pressure as follows (mean systolic +/- SED/mean diastolic +/- SED): (systolic and diastolic, -6.8 +/- 2.1/-3.9 +/- 1.3); day ambulatory blood pressure (diastolic, /-2.8 +/- 1.0); and night ambulatory blood pressure (systolic and diastolic, -4.2 +/- 1.8/-3.9 +/- 1.1). The intraperson variability of the day ambulatory blood pressure (as measured every 15 min) was identical for the smokers and the nonsmokers. Smokers were found to have a diminished "white coat" effect; this diminished white coat effect has not previously been described. The major white coat effect was seen in the older nonsmokers, whereas the diminished white coat effect was most pronounced in the older male smokers and in the younger female smokers. Smokers seem to have a diminished white coat effect, as well as a lower ambulatory blood pressure throughout the day (diastolic) and at night (systolic and diastolic). The similar intraperson variability found in the smokers' and nonsmokers' blood pressure further speaks for a consistently lower blood pressure in smokers as compared with nonsmokers.
K L Mikkelsen; N Wiinberg; A Høegholm; H R Christensen; L E Bang; P E Nielsen; T L Svendsen; J P Kampmann; N H Madsen; M W Bentzon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of hypertension     Volume:  10     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-07-11     Completed Date:  1997-07-11     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  483-91     Citation Subset:  IM    
Bispebjerg University Hospital, Medical Department P, Copenhagen, Denmark.
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MeSH Terms
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory
Cross-Sectional Studies
Heart Rate / physiology*
Middle Aged
Physician-Patient Relations
Stress, Psychological / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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