Document Detail


Smoking and peptic ulcer in rheumatoid arthritis.
MedLine Citation:
PMID:  3698359     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prevalence of chronic peptic ulcer among 152 out-patients with rheumatoid arthritis attending a district general hospital was found to be 16.4% (25 patients), as against 6.6% (10 patients) among an equal number of matched control out-patients with other diagnoses. There was no evidence that any form of anti-inflammatory treatment increased ulcer risk, but smoking was significantly associated with a higher prevalence of ulcer. This relationship was shown to be quantitative and to depend upon an increased frequency of duodenal ulcer in women who smoked. It is possible that greater numbers would have shown the effect of smoking to apply to both sexes, and that for all patients with rheumatoid arthritis abstention from smoking could diminish the high risk of peptic ulceration associated with this disease.
Authors:
J M Willoughby; W K Essigman; J C Weber; R F Pinerua
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  4     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    1986 Jan-Mar
Date Detail:
Created Date:  1986-06-11     Completed Date:  1986-06-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  31-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Arthritis, Rheumatoid / complications*
Female
Humans
Male
Peptic Ulcer / complications*,  epidemiology,  etiology
Risk
Smoking*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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