Document Detail

Smoking-induced olfactory dysfunction in chronic sinusitis and assessment of brief University of Pennsylvania Smell Identification Test and T&T methods.
MedLine Citation:
PMID:  17063734     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To evaluate the outcome of smell activity after endoscopic sinus surgery in chronic sinusitis, it is important to verify evidence of smoking-induced olfactory dysfunction. METHODS: In both the preoperative and the postoperative stages, the 5-odorant T&T olfactometer (T&T5) and the 40-item University of Pennsylvania Smell Identification Test (UPSIT40) were administered to 100 patients (84 men and 16 women; mean age, 49.5 years; range, 21-75 years) who underwent surgery for chronic sinusitis. Additionally, as more simplified measures, we adopted a 3-odorant T&T (T&T3) and a 12-item UPSIT (UPSIT12), and then compared findings with those of each original method. RESULTS: (1) Obvious correlations of scores were noticed both between T&T5 and T&T3 and between UPSIT40 and UPSIT12 (r = 0.964 and 0.893, respectively), (2) significant changes in postoperative scores were observed on all four measurements (p < 0.0001), (3) smoking-induced hyposmia was noticeable in older subjects but not in younger subjects, and (4) the correlations of postoperative scores and the age of smoker or the smoking dose was significant (UPSIT40, r = 0.825 or 0.642; UPSIT12, r = 0.666 or 0.428; T&T5, r = 0.447 or 0.476; T&T3, r = 0.457 or 0.500, respectively). CONCLUSION: The abbreviated measures of T&T3 and UPSIT12 could be available enough to assess the effect of surgical intervention on olfaction, while the original UPSIT40 was considered to be the most sensitive among the four methods tested here for examining the impact of smoking on olfaction.
Kazuko Sugiyama; Yasuhiro Hasegawa; Naruji Sugiyama; Motohiko Suzuki; Nobuhiro Watanabe; Shingo Murakami
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of rhinology     Volume:  20     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-10-26     Completed Date:  2007-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  439-44     Citation Subset:  IM    
Department of Otorhinolaryngology, Nagoya City University Medical School, Nagoya, Japan.
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MeSH Terms
Chronic Disease
Diagnostic Tests, Routine / methods*
Middle Aged
Olfaction Disorders / diagnosis*,  etiology*,  physiopathology
Retrospective Studies
Sinusitis / complications,  surgery
Smoking / adverse effects*

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