Document Detail


Smoking cessation with smokeless tobacco and group therapy: an open, randomized, controlled trial.
MedLine Citation:
PMID:  18686184     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Smokeless tobacco might be effective as an adjunct for smoking cessation. We evaluated the efficacy of smokeless tobacco and group support for smoking cessation in an open, randomized study that compared smokeless tobacco plus group support versus group support only. The study enrolled 263 healthy smokers (M (age) = 49 years) who smoked a mean of 24 cigarettes/day, with a mean of 31 pack-years. Smokeless tobacco was provided for 7 weeks (or up to 12), combined with eight group support visits provided by nurses. The control group received group support only. Smoking cessation rates were statistically significantly better in the smokeless tobacco group than in the control group during the first 7 weeks. Point-prevalence abstinence rates at 7 weeks were 36.4% versus 20.8% (OR = 2.52, p = .001), respectively; and continuous abstinence rates from weeks 4 to 7 were 31.5% versus 19.2% (OR = 1.94, p = .023), respectively. The primary outcomes (i.e., 6-month point prevalence) were 23.1% versus 20.8%, respectively (OR = 1.31, ns). Smokeless tobacco was relatively well tolerated, although 15 subjects (11.2%) stopped use due to adverse events. A total of 25 subjects (17.5 %) were still using smokeless tobacco after 6 months. This trial demonstrated short-term efficacy of smokeless tobacco in combination with group support for smoking cessation but no long-term efficacy.
Authors:
Philip Tønnesen; Kim Mikkelsen; Linda Bremann
Related Documents :
14705374 - Oral hygiene, dietary pattern and smoking habits of bedouin (nomadic arabs) population ...
11899594 - Factors influencing the age at which adolescents start smoking. a comparison between a ...
11446494 - Circadian variation of the onset of acute myocardial infarction in the osaka area, 1998...
11817764 - Adolescent antisocial behavior and substance use: longitudinal analyses.
15378804 - Another look at heavy episodic drinking and alcohol use disorders among college and non...
21282964 - Nationwide population-based epidemiologic study of cryptococcal meningitis in taiwan.
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco     Volume:  10     ISSN:  1462-2203     ISO Abbreviation:  Nicotine Tob. Res.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-07     Completed Date:  2009-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815751     Medline TA:  Nicotine Tob Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1365-72     Citation Subset:  IM    
Affiliation:
Department of Pulmonary Medicine, Gentofte Hospital, Niels Andersenvej 65, Hellerup, Denmark. d144002@dadlnet.dk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Chewing Gum*
Denmark
Follow-Up Studies
Humans
Male
Middle Aged
Nicotine / blood
Patient Satisfaction / statistics & numerical data
Time Factors
Tobacco Use Cessation / methods*
Tobacco Use Disorder / blood,  drug therapy*
Tobacco, Smokeless*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Chewing Gum; 54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Safe babies: a qualitative analysis of the determinants of postpartum smoke-free and relapse states.
Next Document:  Smoking during pregnancy in ethnic populations: the Generation R study.