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Smoking as a risk factor for intraoperative hypoxemia during one lung ventilation.
MedLine Citation:
PMID:  23377503     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Smoking is associated with many intra and postoperative events, especially respiratory complications. Hypoxemia and airway damage are found to aggravate any pre-existing respiratory pathology among smokers. One lung ventilation (OLV) carries a 4-10 % risk of development of hypoxia. AIM: The purpose of this study was to predict the incidence of hypoxemia for smokers during OLV for patients undergoing video-assisted thoracoscopic surgery (VATS). PATIENTS AND METHODS: Sixty patients undergoing VATS using OLV by double lumen tube were included in this pilot cross-sectional study. These patients were divided into 2 groups, group S which included 30 heavy smoker patients (smoking more than 20 cigarettes per day for more than 20 years) and group NS which included 30 non-smoker patients. Intra and postoperative arterial oxygen tension (PaO(2)), arterial carbon dioxide tension (PaCO(2)), and intraoperative peak airway pressure were compared between the 2 groups. RESULTS: PaO(2) was significantly higher in the non-smoker group than in the smoker group, both at the start and end of OLV. It was 173 ± 68 mmHg for NS compared with 74 ± 10.8 mmHg for S at the start of OLV; at the end of OLV it was 410 ± 78 mmHg for the former and 360 ± 72 mmHg for the latter (P < 0.05). CONCLUSION: From this study it can be concluded that for heavy smoker patients there was a significant reduction in arterial oxygen tension (PaO(2)) in comparison with non-smokers. However, hypoxemia reported for both groups was comparable.
Authors:
Mohamed A Khalil
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-3
Journal Detail:
Title:  Journal of anesthesia     Volume:  -     ISSN:  1438-8359     ISO Abbreviation:  J Anesth     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8905667     Medline TA:  J Anesth     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Anesthesia, Faculty of Medicine, Cairo University, Giza, Egypt, mohamedkhalil404@hotmail.com.
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