Document Detail


Smoking and acute urinary retention: the Olmsted County study of urinary symptoms and health status among men.
MedLine Citation:
PMID:  19152343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Previous reports have suggested an inverse relationship between smoking and surgery for benign prostatic hyperplasia (BPH). We hypothesized that acute urinary retention (AUR), an adverse outcome of this disease and indication for surgical treatment, may be related to smoking.
METHODS: Study subjects were randomly selected from Olmsted County men aged 40-79 identified through the Rochester Epidemiology Project. Of the 3,854 eligible men, 2,089 (54%) completed a questionnaire that included the American Urological Association Symptom Score and assessed smoking status. Community medical records were examined for occurrence of AUR with documented catheterization in the subsequent 10 years and occurrence of BPH surgery. Proportional hazard models were used to assess the relationship between baseline smoking status and subsequent retention.
RESULTS: In the 18,307 person-years of follow-up, 114 men had AUR. When compared to 727 never-smokers, there was a trend among the 336 current smokers to be at lower risk (Relative risk (RR) = 0.62, 95% Confidence Interval (CI) = 0.33, 1.18) whereas the 1,026 former smokers were at similar risk to non-smokers (RR = 1.0, 95%CI = 0.67, 1.46). Among men with moderate-severe symptoms at baseline, current smokers were at lower risk of retention compared to non-smokers (RR = 0.65, 95%CI = 0.22, 1.91) but the association approached the null among those with none-mild symptoms (RR = 0.91, 95% CI = 0.40, 2.06).
CONCLUSIONS: Community-dwelling men who currently smoke may be at a modestly reduced risk of AUR. The magnitude of this association is sufficiently small that it seems unlikely that this explains a sizable proportion of the inverse association between smoking and surgically treated BPH.
Authors:
Aruna V Sarma; Debra J Jacobson; Jennifer L St Sauver; Michael M Lieber; Cynthia J Girman; Ajay Nehra; Steven J Jacobsen
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Prostate     Volume:  69     ISSN:  1097-0045     ISO Abbreviation:  Prostate     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-20     Completed Date:  2009-05-04     Revised Date:  2014-09-14    
Medline Journal Info:
Nlm Unique ID:  8101368     Medline TA:  Prostate     Country:  United States    
Other Details:
Languages:  eng     Pagination:  699-705     Citation Subset:  IM    
Copyright Information:
2009 Wiley-Liss, Inc.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cohort Studies
Follow-Up Studies
Humans
Male
Middle Aged
Minnesota / epidemiology
Proportional Hazards Models
Prospective Studies
Prostatic Hyperplasia / epidemiology*,  surgery
Questionnaires
Smoking / epidemiology*
Urinary Retention / epidemiology*
Grant Support
ID/Acronym/Agency:
AR30582/AR/NIAMS NIH HHS; DK58859/DK/NIDDK NIH HHS; R01 AR030582/AR/NIAMS NIH HHS; R01 DK058859/DK/NIDDK NIH HHS; R01 DK058859-10/DK/NIDDK NIH HHS
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