Document Detail

Smoking may be a harbinger of early failure with ultraporous metal acetabular reconstruction.
MedLine Citation:
PMID:  23292885     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Smoking is considered a risk factor for surgical complications in total hip arthroplasty (THA) and has been linked to a higher rate of aseptic loosening in uncemented acetabular components. Acetabular reconstruction with newer ultraporous metals in both complex primary and revision THA has increased survivorship but it is unclear whether smoking affects survival of these implants.
QUESTIONS/PURPOSES: We reviewed our early experience with THA using ultraporous acetabular components to assess the incidence and etiology of early failure and examine if any preoperative variables, including smoking, related to failure.
METHODS: We used ultraporous acetabular components in 498 patients (534 hips), beginning with one case each in 1999 and 2004, 17 in 2005, and the majority from 2006 through March 2010. There were 159 complex primary and 375 revision cases. Of these patients, 17% were smokers (averaging 35 pack-years), 31% previous smokers (averaging 29 pack-years), 41% nonsmokers, and 1% unknown. Failure modes possibly related to smoking were infection, aseptic loosening, or periacetabular fracture and unrelated were dislocation and implant breakage. Minimum followup was 1 month (average, 32 months; range, 1-78 months).
RESULTS: There were 34 cup failures (6%): 17 infections, 14 aseptic loosening, and one each liner breakage, dislocation, and periacetabular fracture. The failure rate (uncontrolled for potentially confounding variables) was 10% in both current (9 of 89) and prior smokers (17 of 167) and 3% in nonsmokers 8 of 271).
CONCLUSION: With ultraporous metal technology in complex primary and revision THA, smoking, both past and current, may be a risk factor for early failure.
LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Adolph V Lombardi; Keith R Berend; Joanne B Adams; Ryan C Jefferson; Michael A Sneller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  471     ISSN:  1528-1132     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-21     Completed Date:  2013-05-28     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  486-97     Citation Subset:  AIM; IM    
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MeSH Terms
Acetabulum / surgery
Aged, 80 and over
Arthroplasty, Replacement, Hip
Hip Joint / surgery
Hip Prosthesis*
Middle Aged
Prosthesis Design
Prosthesis Failure / etiology*
Risk Factors
Smoking / adverse effects*
Reg. No./Substance:

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