Document Detail

Smears in the diagnosis of pituitary adenomas.
MedLine Citation:
PMID:  9622677     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To review the cytomorphologic picture of pituitary adenomas as revealed by intraoperative smear preparation and to note features useful in differential diagnosis from other sellar tumors. STUDY DESIGN: A total of 46 pituitary adenomas in which intraoperative smears were available were reviewed. All tumors were subsequently examined by paraffin section and immunohistochemistry. RESULTS: The important cytologic appearances were epithelial cords and sheets with dyscohesive ends, acini and papillary formations. Cytoplasmic contents, depending on functional status, were variably clear, with vacuolation or eosinophilic bodies and occasional paranuclear bodies. Mild cellular pleomorphism and binucleate forms were common. CONCLUSIONS: Pituitary adenomas possess distinct cytologic features that are important in intraoperative differential diagnoses from normal pituitary tissues, germinomas, meningiomas, craniopharyngiomas and oligodendrogliomas.
H K Ng
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  42     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1998 May-Jun
Date Detail:
Created Date:  1998-06-18     Completed Date:  1998-06-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  614-8     Citation Subset:  IM    
Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong.
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MeSH Terms
Adenoma / diagnosis,  pathology*,  surgery
Craniopharyngioma / diagnosis
Diagnosis, Differential
Dysgerminoma / diagnosis
Epithelial Cells / pathology
Frozen Sections
Inclusion Bodies / ultrastructure
Intraoperative Care / methods*
Meningioma / diagnosis
Middle Aged
Oligodendroglioma / diagnosis
Pituitary Neoplasms / diagnosis,  pathology*,  surgery
Prolactinoma / diagnosis,  pathology,  surgery
Retrospective Studies
Specimen Handling / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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