| Smallpox and pregnancy: from eradicated disease to bioterrorist threat. | |
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MedLine Citation:
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PMID: 12100808 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Health care personnel must be prepared for the threat of bioterrorism. Our objective is to educate primary care providers, obstetricians in particular, in the prevention, diagnosis, and treatment of smallpox. Smallpox poses a particularly serious threat because of its high case-fatality rate in unvaccinated populations (no one younger than 25 years has been vaccinated, and older persons have little remaining residual immunity). Routine nonemergency smallpox vaccination is restricted to laboratory staff working with smallpox-related viruses. Under these circumstances, contraindications to vaccination are pregnancy, immunodeficiency, exfoliative skin conditions (eczema), and allergy to vaccine components. In case of an intentional release of the smallpox virus, those directly exposed and their close contacts must be vaccinated and isolated. Under such emergency circumstances, pregnant women exposed to the variola virus should be vaccinated because of the lethality of the disease during pregnancy. Currently, there is a limited supply of vaccine available. |
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Authors:
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Victor R Suarez; Gary D V Hankins |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 100 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2002 Jul |
Date Detail:
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Created Date: 2002-07-08 Completed Date: 2002-08-02 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 87-93 Citation Subset: AIM; IM |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston 77555-0587, USA. vrsuarez@utmb.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bioterrorism / prevention & control* Emergencies Female Humans Middle Aged Pregnancy Pregnancy Complications, Infectious / mortality, prevention & control* Primary Prevention / organization & administration Prognosis Risk Assessment Risk Factors Smallpox / mortality, prevention & control* Smallpox Vaccine / administration & dosage*, adverse effects Survival Rate Vaccination / standards* |
| Chemical | |
Reg. No./Substance:
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0/Smallpox Vaccine |
| Comments/Corrections | |
Comment In:
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Obstet Gynecol. 2002 Dec;100(6):1356; author reply 1356
[PMID:
12468187
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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